Bioinformatics Algorithms: Techniques and Applications Hardcover - 2008 - 1st Edition
by Ion Mandoiu; Alexander Zelikovsky
From the rear cover
Presents algorithmic techniques for solving problems in bioinformatics, including applications that shed new light on molecular biology
This book introduces algorithmic techniques in bioinformatics, emphasizing their application to solving novel problems in post-genomic molecular biology. Beginning with a thought-provoking discussion on the role of algorithms in twenty-first-century bioinformatics education, Bioinformatics Algorithms covers:
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General algorithmic techniques, including dynamic programming, graph-theoretical methods, hidden Markov models, the fast Fourier transform, seeding, and approximation algorithms
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Algorithms and tools for genome and sequence analysis, including formal and approximate models for gene clusters, advanced algorithms for non-overlapping local alignments and genome tilings, multiplex PCR primer set selection, and sequence/network motif finding
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Microarray design and analysis, including algorithms for microarray physical design, missing value imputation, and meta-analysis of gene expression data
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Algorithmic issues arising in the analysis of genetic variation across human population, including computational inference of haplotypes from genotype data and disease association search in case/control epidemiologic studies
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Algorithmic approaches in structural and systems biology, including topological and structural classification in biochemistry, and prediction of protein-protein and domain-domain interactions
Each chapter begins with a self-contained introduction to a computational problem; continues with a brief review of the existing literature on the subject and an in-depth description of recent algorithmic and methodological developments; and concludes with a brief experimental study and a discussion of open research challenges. This clear and approachable presentation makes the book appropriate for researchers, practitioners, and graduate students alike.
Ion I. M?Andoiu, PhD, is Assistant Professor in the Computer Science and Engineering Department at the University of Connecticut. His research focuses on the design and analysis of exact and approximation algorithms for NP-hard optimization problems, particularly in the areas of bioinfor-matics and computational molecular biology, VLSI computer-aided design and manufacturing, and ad-hoc wireless networks.
Details
- Title Bioinformatics Algorithms: Techniques and Applications
- Author Ion Mandoiu; Alexander Zelikovsky
- Binding Hardcover
- Edition number 1st
- Edition 1
- Pages 528
- Volumes 1
- Language ENG
- Publisher Wiley-Interscience
- Date 2008-02-01
- Features Bibliography, Index, Table of Contents
- ISBN 9780470097731 / 0470097736
- Weight 1.89 lbs (0.86 kg)
- Dimensions 9.42 x 6.29 x 1.19 in (23.93 x 15.98 x 3.02 cm)
- Library of Congress subjects Bioinformatics, Algorithms
- Library of Congress Catalog Number 2007034307
- Dewey Decimal Code 572.802
Media reviews
Citations
- Scitech Book News, 06/01/2008, Page 53
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Bioinformatics Algorithms
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Bioinformatics Algorithms: Techniques and Applications (Wiley Series in Bioinformatics)
by Mandoiu, Ion; Zelikovsky, Alexander
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