The Mechanism of Mendelian Heredity by Morgan, T.H., Sturtevant, A.H., Muller, H.J. and Bridges, C.B - 1922

New York: Henry Holt and Co., 1922. Second (revised) edition.

1922 UPDATE OF THE 1915 "EPOCH-MAKING BOOK" BY NOBEL LAUREATE T.H. MORGAN AND DISCIPLES THAT LAID THE FOUNDATION FOR THE NEW GENETICS.

8 1/2 inches tall hardcover, red cloth binding, gilt title to spine, frontis diagram of gene distribution on fruit fly chromosomes, i-xiv, 357 pp, 73 figures. Library numbers bottom of spine, embossed institutional library stamp to title page, library sticker and pocket to back paste-down, binding tight, text bright and unmarked, good+ in custom archival myar cover. PREFACE TO SECOND EDITION We have tried to bring the book up to date not only by adding here and there throughout the text the latest results on the subject, but also by adding entirely new chapters, and new maps of the best known mutant factors. Much new material las been added to the chapter on sex; the chapter on selection has been largely rewritten. The new chapters are one on heredity in Protozoa, and one on mutation in the evening primrose. In the latter field, the latest results of de Vries and others on Oenothera, and the work on balanced lethals bid fair to bring the earlier discoveries of de Vries into hne with more recent work in the whole field of mutation and inheritance. In place of the "Appendix" we have prepared a small manual for laboratory use (Henry Holt and Co., Publishers) that gives directions for carrying out genetic experiments with the pomace fly. These experiments have been picked out as the ones most suitable for student work, and also because thev serve to illustrate, in a practical way, most of the fundamental principles of heredity. In addition, the newest culture methods for breeding Drosophila are given, as well as other methods of handling this material. GARRISON-MORTON 246 (First edition, 1915). "Summarizes the major early findings of Morgan's Drosophila research group, which based its research on the rapidly reproducing small vinegar fly, Drosophila melanogaster, often called the fruit fly. This epoch-making book presented evidence that genes were arranged linearly on chromosomes, and that the Mendelian laws could be shown to be based on observable events occurring in cells. The group also showed that heredity could be studied rigorously and quantitatively. Morgan was awarded the Nobel Prize for Physiology or Medicine in 1933." Geneticist Curt Stern called the book "the fundamental textbook of the new genetics" and C. H. Waddington noted that "Morgan's theory of the chromosome" represents a great leap of imagination comparable with Galileo or Newton". THOMAS HUNT MORGAN (1866 - 1945) was an American embryologist, geneticist, and evolutionary biologist who won the Nobel Prize in Physiology or Medicine in 1933 for discoveries elucidating the role that the chromosome plays in heredity. Morgan received his Ph.D. from Johns Hopkins University in zoology in 1890 and researched embryology during his tenure at Bryn Mawr. Following the rediscovery of Mendelian inheritance in 1900, Morgan began to study the genetic characteristics of the fruit fly Drosophila melanogaster. In his famous Fly Room at Columbia University, Morgan demonstrated that genes are carried on chromosomes and are the mechanical basis of heredity. These discoveries formed the basis of the modern science of genetics.