Magic Bullets To Conquer Malaria: from Quinine to Qinghaosu

ASM Press, 2013-11-19. Paperback. Like New. 2013 ASM Press (Washington, D.C.), 6 x 9 inches tall trade paperback, illustrated with structural formulas, xiii, 298 pp. A near fine book, with no noted detractions, seemingly unopened. ~WWW~ [1.5P] Provides a historical overview of the medicines that have been used to treat malaria. It recounts how these drugs were discovered, how they have been used, and why they have failed to eradicate this disease. In addition, readers will learn about the use of larvicides, bednets, and DDT as well as recombinant DNA and monoclonal antibodies to block malaria transmission from mosquitoes to humans. This book will help microbiologists, parasitologists, pharmacologists, medicinal chemists, biochemists, physicians, and drug researchers better understand what has been done and what still needs to be done in the battle against malaria. C ontents: From breathing bad air to biting beasts; Myth to medicine : quinine; Synthetic dyes to drugs : atabrine and chloroquine; Antimicrobials to antimalarials : prontosil, pyrimethamine, proguanil, and atovaquone; To destroy liver stages : primaquine and tafenoquine; Quinine to mefloquine; Reversal of fortune; Sweet wormwood of success : qinghaosu; Antibiotics and the apicoplast; A possible dream : control by blocking transmission; The dream of eradication; A reasonable dream.