De Aere, aquis, & locis, Liber olim mancus, nunc integer:qui Galendo, De habitationibus, & aquis, & temporibus & regionibus inscribitur: Ab Adriano Alemano apud Parisios medico, commentariis quatuor illustrates.

Paris: Gilles Gorbin, 1557. First Edition with the Latin translation and commentary of Adrian l'Alemant. It is preceded by the 1529 edition with translation and commentary by Janus Cornarius. Stillwell mentions a 1542 edition but it is not listed in the other bibliographies or on Worldcat. "The first book ever written on medical geography, climatology, and anthropology." (G & M) "In the book Airs, Waters, and Places, […] written by Greek physician Hippocrates in the 5th or 4th century bce, the first systematic attempt was made to set forth a causal relationship between human diseases and the environment. Until the new sciences of bacteriology and immunology emerged well into the 19th century, this book provided a theoretical basis for the comprehension of endemic disease (that persisting in a particular locality) and epidemic disease (that affecting a number of people within a relatively short period)." (Encyc. Britannica) "In addition to being the earliest known recognition of the action of climate on health, the text gives a comparison of the climatic conditions of Europe and Asia and their differences in flora and fauna." (Stillwell) Adams H596. BM STC French p. 226. Durling 2403. Wellcome 3202. cfGarrison & Morton, 4th Edn., 1767 (1923 English version in his Works). cfStillwell, The Awakening Interest in Science, 658. 8vo. ff. 8 (the last blank), 230, [18]. errata on verso of last leaf. text in Greek & Latin. early 20th century half pigskin (slight staining in upper margins of last gatherings). elala5653