Quantitative Trait Loci: Methods and Protocols Hardcover - 2002
by Nicola J. Camp (Editor); Angela Cox (Editor)
First line
A classical case-control study design is frequently used in genetic epidemiology to investigate the association between genotype and the presence or absence of disease.
From the rear cover
Statistical methods for the analysis of quantitative trait locus (QTL), in conjunction with genome-wide screening technologies, are today yielding exciting results in the study of human disease, experimental organisms, and agriculture. In Quantitative Trait Loci: Methods and Protocols, Drs. Nicola Camp and Angela Cox have assembled a highly experienced panel of statistical geneticists who demonstrate in a step-by-step fashion how to use this powerful methodology and associated software for the detection and fine mapping of quantitative trait loci. Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and useful variations and/or extensions to standard methods are included that ease the reader toward understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov chain Monte Carlo method for joint linkage and segregation analysis.
Up-to-date and highly practical, Quantitative Trait Loci: Methods and Protocols makes available to nonmathematical investigators a step-by-step guide to the productive use today of all the latest techniques for localizing genes involved in complex quantitative traits.
Details
- Title Quantitative Trait Loci: Methods and Protocols
- Author Nicola J. Camp (Editor); Angela Cox (Editor)
- Binding Hardcover
- Edition U. S. EDITION
- Pages 360
- Volumes 1
- Language ENG
- Publisher Humana, USA
- Date 2002-04-26
- Illustrated Yes
- Features Bibliography, Illustrated, Index
- ISBN 9780896039278 / 0896039277
- Weight 1.63 lbs (0.74 kg)
- Dimensions 9.28 x 6.26 x 1.16 in (23.57 x 15.90 x 2.95 cm)
- Library of Congress subjects Gene mapping, Phenotype
- Library of Congress Catalog Number 2001039828
- Dewey Decimal Code 576.507
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